Management of giant cell tumor of bone in the era of denosumab: A case series and review of the literature

Authors

DOI:

https://doi.org/10.3126/ajms.v14i1.48969

Keywords:

Giant cell tumor; Bone; Denosumab; Radiotherapy

Abstract

Giant cell tumor (GCT) of the bone also known as osteoclastoma typically arises from the meta-epiphyseal region of the long bone and comprises 5% of all bone tumors and 20% of benign bone tumors. Understanding pathogenesis is the key to successful systemic therapy with denosumab, a RANK-ligand inhibitor. In this context, we report seven GCT bone-treated denosumab and radiotherapy cases with a diverse clinical presentation from our institute, NRS Medical College, and Hospital Kolkata.

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Published

2023-01-01

How to Cite

Anjan Bera, Shatarupa Dutta, Aparajita Sadhya, Soham Gangopadhyay, Debosmita Bhattacharyya, Srikrishna Mandal, & Manna, D. (2023). Management of giant cell tumor of bone in the era of denosumab: A case series and review of the literature. Asian Journal of Medical Sciences, 14(1), 238–242. https://doi.org/10.3126/ajms.v14i1.48969

Issue

Section

Case Series