Association between vitamin D and C-reactive protein level in post-COVID recovery period

Authors

  • Sisir Chakraborty Associate Professor, Department of Medicine, College of Medicine and Sagore Dutta Hospital, Kolkata, West Bengal, India https://orcid.org/0000-0002-8483-9406
  • Sanchayan Sinha Demonstrator, Department of Biochemistry, College of Medicine and Sagore Dutta Hospital, Kolkata, West Bengal, India https://orcid.org/0000-0001-9061-9824
  • Soumita Ghosh Sengupta Associate Professor, Department of Pathology, College of Medicine and Sagore Dutta Hospital, Kolkata, West Bengal, India
  • Satwika Sinha Associate Professor, Department of Biochemistry, College of Medicine and Sagore Dutta Hospital, Kolkata, West Bengal, India https://orcid.org/0000-0002-0968-0319
  • Indranil Chakraborty Professor, Department of Biochemistry, College of Medicine and Sagore Dutta Hospital, Kolkata, West Bengal, India https://orcid.org/0000-0003-0135-2270

DOI:

https://doi.org/10.3126/ajms.v14i2.48881

Keywords:

Vitamin D; COVID; D-dimer; C-reactive protein

Abstract

Background: Severe acute respiratory distress syndrome coronavirus 2 pandemic shows a spectrum of symptoms and complications which are variably dependent on individual’s immune status. Vitamin D deficiency, often preexisting, causes poor prognosis in the post-COVID recovery phase of the survivors characterized by increased C-reactive protein (CRP) and decreased D-dimer levels.

Aims and Objectives: The aims of this study were to find any correlation exists between vitamin D level and inflammatory marker CRP and D-dimer in post-COVID period.

Materials and Methods: Seventy post-COVID recovery patients from the follow-up medicine outpatient department of College of Medicine and Sagore Dutta Hospital were tested for vitamin D, D-dimer, and serum CRP levels.

Results: CRP levels of patients with lower vitamin D level (<20 ng/ml) were significantly higher (P<0.001) than the patients with higher vitamin D level. The D-dimer levels of vitamin D deficient group found to be significantly higher than the other group. There is statistically significant negative correlation found between CRP and vitamin D level and significant positive correlation has been found between D-dimer and vitamin D (P<0.001).

Conclusion: Vitamin D may have an important role in recovery stage of COVID patients.

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Author Biography

Satwika Sinha, Associate Professor, Department of Biochemistry, College of Medicine and Sagore Dutta Hospital, Kolkata, West Bengal, India

Assistant Profrssor.Department Of Biochemistry

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Published

2023-02-01

How to Cite

Chakraborty, S., Sinha, S., Ghosh Sengupta, S., Satwika Sinha, & Chakraborty, I. (2023). Association between vitamin D and C-reactive protein level in post-COVID recovery period. Asian Journal of Medical Sciences, 14(2), 28–31. https://doi.org/10.3126/ajms.v14i2.48881

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Original Articles