Relationship between maternal Vitamin D levels and neonatal Vitamin D levels with delayed neonatal hypocalcemia - A hospital-based observational study
DOI:
https://doi.org/10.3126/ajms.v14i2.48612Keywords:
Delayed hypocalcemia; Vitamin D deficiency; Hyperphosphatemia; Mother-infant pairAbstract
Background: Vitamin D has important role in regulating various metabolic processes in the body including calcium metabolism. Fetuses and neonates are dependent on their mothers to get adequate supply of Vitamin D. Maintaining adequate maternal Vitamin D levels may be highly beneficial for their fetuses and the babies.
Aims and Objectives: The aim of the study was to find a correlation, if any, between maternal Vitamin D status and neonatal Vitamin D levels and delayed neonatal hypocalcemia.
Materials and Methods: Fifty mother infant pairs with neonatal late onset hypocalcemia were included in the study. Detailed clinical history along with simultaneous maternal and neonatal blood samples were taken for estimation of calcium, phosphorus, parathormone (intact), and Vitamin D levels.
Results: Mean maternal and neonatal serum Vitamin D (25-OH Vitamin D) levels were 19.5±7.5 and 15±8.5, respectively. There was a statistically significant correlation between maternal and neonatal Vitamin D levels (P=0.001). There was also a direct correlation between low maternal Vitamin D levels and delayed hypocalcemia in neonates (P=0.048). Mean maternal and neonatal serum calcium levels were 9±1.5 mg/dl and 6.2±0.4 mg/dl, respectively. There was no significant statistical correlation between the two (P>0.05).
Conclusion: Maternal Vitamin D level appears to be an important determinant of neonatal Vitamin D and serum calcium levels.
Downloads
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2022 Asian Journal of Medical Sciences
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Authors who publish with this journal agree to the following terms:
- The journal holds copyright and publishes the work under a Creative Commons CC-BY-NC license that permits use, distribution and reprduction in any medium, provided the original work is properly cited and is not used for commercial purposes. The journal should be recognised as the original publisher of this work.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).