Nasal basal cell carcinoma in xeroderma pigmentosum - diagnosis, workup, management, and reconstruction
DOI:
https://doi.org/10.3126/ajms.v13i5.41345Keywords:
Basal cell carcinoma, Histopathological, Incisional biopsy, Sun protection, Xeroderma pigmentosumAbstract
Xeroderma pigmentosum (XP) is genetic autosomal recessive disorder with photosensitivity on exposure to sun and also presents with various malignancies such as squamous cell carcinoma, basal cell carcinoma, and malignant melanoma. A 22-year-old female visited our outpatient clinic with 18 months history of pigmented nodule on her nose. She was diagnosed with XP since she was 2 years old. Physical examination revealed a waxy, blackish-brown nodule on her nose. Incisional biopsy was performed. The histological findings revealed multiple, palisaded basophilic tumor masses surrounded by prominent infiltrating lymphocytes confirming our clinical diagnosis. She was advised sun protection with the use of protective clothing and glasses. XP leads to chances of various malignancies. Early diagnosis, proper clinical examination, histopathological examination for the diagnosis of condition is must to come to proper diagnosis. Instructions to the patients to take proper protection from sun and wearing protective clothing must be given.
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