ANI scoring system – In differentiating alcoholic and non-alcoholic liver disease

Authors

  • Anitha G Assistant Professor, Department of Biochemistry, Sri Venkateshwaraa Medical College and Hospital and Research Centre, Puducherry https://orcid.org/0000-0003-3884-1131
  • Sivakumar J Associate Professor, Department of Biochemistry, Dhanalakshmi Srinivasan Medical College and Hospital, Perambalur https://orcid.org/0000-0002-6944-7439
  • Kalavathy Ponniraivan Former Head and Professor, Department of Biochemistry, Trichy SRM Medical College and Hospital, Trichy, Tamil Nadu, India

DOI:

https://doi.org/10.3126/ajms.v12i11.38868

Keywords:

Alcoholic liver disease, Non-alcoholic fatty liver disease, ANI Score

Abstract

Background: Alcoholic liver disease/non-alcoholic liver disease Index – ANI scoring system was constructed for clinically diagnosing the etiology of liver diseases, avoiding the risks of liver biopsy.

Aims and Objectives: This study aims to test the reliability of ANI scoring system as a non-invasive method to distinguish alcoholic liver disease (ALD) from non-alcoholic fatty liver disease (NAFLD).

Materials and Methods: This retrospective study was conducted on 177 (114 men and 58 women) treated as inpatients in Trichy SRM Medical College Hospital and Research Centre, Trichy, in the period of December 1, 2015–August 1, 2016. About 40 patients with etiology of viral, autoimmune, and biliary lithiasis were excluded. A total of 137 patients (98 men and 39 women) were classified into two groups, ALD (70) and NAFLD (67) based on diagnosis. Parameters of ANI – AST, ALT, MCV, BMI, and sex were recorded. ANI was calculated by online calculator.

Results: ANI was significantly higher in patients with ALD than NAFLD (P<0.01). The cutoff value of ANI is –0.11.

Conclusion: On the basis of the results, ANI scoring system may be used in clinically distinguishing ALD from NAFLD, avoiding the risks of liver biopsy.

Downloads

Download data is not yet available.
Abstract
325
PDF
529

Downloads

Published

2021-11-01

How to Cite

Anitha G, Sivakumar J, & Ponniraivan, K. (2021). ANI scoring system – In differentiating alcoholic and non-alcoholic liver disease. Asian Journal of Medical Sciences, 12(11), 104–107. https://doi.org/10.3126/ajms.v12i11.38868

Issue

Vol. 12 No. 11 (2021)

Section

Original Articles

License

Copyright (c) 2021 Asian Journal of Medical Sciences

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Authors who publish with this journal agree to the following terms:

  1. The journal holds copyright and publishes the work under a Creative Commons CC-BY-NC license that permits use, distribution and reprduction in any medium, provided the original work is properly cited and is not used for commercial purposes. The journal should be recognised as the original publisher of this work.
  2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
  3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).