A Review of Malaria Diagnostic Tools: Microscopy and Rapid Diagnostic Test

Authors

  • Vyankatesh T Anchinmane Department of Pathology, Topiwala National Medical College & B. Y. L. Nair Ch. Hospital, Mumbai Central
  • Rakesh T Shedge Department of Pathology, Topiwala National Medical College & B. Y. L. Nair Ch. Hospital, Mumbai Central

DOI:

https://doi.org/10.3126/ajms.v1i2.2965

Keywords:

Malarial parasite, QDx MALARIA PAN / Pf rapid immunochromatograpic card test, blood smear

Abstract

Objective: Microscopic detection of parasites has been the reference standard for malaria diagnosis for decades. However, difficulty in maintaining required technical skills and infrastructure has spurred the development of non-microscopic malaria rapid diagnostic devices based on the detection of malaria parasite antigen. We evaluated the QDx MALARIA PAN/Pf rapid immunochromatograpic card test by comparing it with the conventional standard blood smear method for the detection of malaria.
Material & Methods: A total of 325 specimens of blood from cases of fever (falciparum malaria 88, vivax malaria 168, mixed infection of falciparum and vivax malaria 44, controls 25) were investigated by QDx Malaria Rapid test and blood smear method.
Results: The QDx Malaria Rapid test showed 96.6% sensitivity, 100% specificity and 96.9 % accuracy. However, these parameters were lower when the parasitaemia was less than 500 parasites /μL.
Conclusion: QDx Malaria Rapid test was found to have enormous advantages over smear examination due to its high degree of sensitivity, specificity, speed and ease of performance.

Key Words: Malarial parasite; QDx MALARIA PAN / Pf rapid immunochromatograpic card test; blood smear

DOI: 10.3126/ajms.v1i2.2965

Asian Journal of Medical Sciences 1 (2010) 75-79

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Author Biographies

Vyankatesh T Anchinmane, Department of Pathology, Topiwala National Medical College & B. Y. L. Nair Ch. Hospital, Mumbai Central

Rakesh T Shedge, Department of Pathology, Topiwala National Medical College & B. Y. L. Nair Ch. Hospital, Mumbai Central

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Published

2011-01-14

How to Cite

Anchinmane, V. T., & Shedge, R. T. (2011). A Review of Malaria Diagnostic Tools: Microscopy and Rapid Diagnostic Test. Asian Journal of Medical Sciences, 1(2), 75–79. https://doi.org/10.3126/ajms.v1i2.2965

Issue

Vol. 1 No. 2 (2010)

Section

Original Articles

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