Urinary iodine in second trimester of pregnancy: A cross sectional study in tertiary care hospital of Belagavi

Authors

  • Bibek Basnet Post Graduate Student, Department of Biochemistry, KLE Academy of Higher Education and Research, Jawaharlal Nehru Medical College, Belagavi, Karnataka, India https://orcid.org/0000-0001-8464-2315
  • Anuradha Patil Professor & Head, Department of Biochemistry, KLE Academy of Higher Education and Research, Jawaharlal Nehru Medical College, Belagavi, Karnataka, India
  • Shridevi Metgud Assistant Professor, Department of Obstetrics and Gynaecology, KLE Academy of Higher Education and Research, Jawaharlal Nehru Medical College, Belagavi, Karnataka, India
  • Lokjan Singh Post Graduate student, Department of Microbiology, KLE Academy of Higher Education and Research, Jawaharlal Nehru Medical College, Belagavi, Karnataka, India
  • Keshab Parajuli Lecturer, Department of Public Health, Asian College for Advance Studies, Purbanchal University, Nepal
  • Bikram Basnet Department of Radiology, University of South China, Hengyang, Hunan, China

DOI:

https://doi.org/10.3126/ajms.v11i5.29439

Keywords:

Urinary Iodine, Pregnancy, ammomiun persulfate, TSH

Abstract

Background: Iodine is a nutritionally important trace element and its deficiency is a common health problem affecting a huge population, particularly pregnant women and children. The physiological role of iodine in the human body is synthesis of thyroid hormones. Thyroxine is approximately 60% iodine by weight. If iodine intake falls below approximately 100μg/day, Thyroid Stimulating Hormone (TSH) secretion is augmented, which increases plasma inorganic iodide clearance.

Aims and Objective: To correlate urinary iodine with serum TSH in the second trimester of pregnant women.

Material and Methods: One hundred five subjects were included in the study from tertiary care hospital. A random urine sample was collected. Iodine was estimated by ammonium persulfate method and TSH values were collected from the OBG department of the subjects enrolled. Statistics: Pearson correlation coefficient was done.

Results: Median UI 138.50 (29.80-350.51) μg/L, median TSH 1.90(0.17-7.46) mIU/L. There was no significant correlation between UI and serum TSH with r = (0.0873, (p = 0.3756).

Conclusion: Urinary iodine is a marker for population iodine status. A preferable biomarker is necessary to know the iodine status of individual which include not only nutritional biomarker and also required to organise reference range for TSH.

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Published

2020-09-01

How to Cite

Basnet, B., Patil, A., Metgud, S., Singh, L., Parajuli, K., & Basnet, B. (2020). Urinary iodine in second trimester of pregnancy: A cross sectional study in tertiary care hospital of Belagavi. Asian Journal of Medical Sciences, 11(5), 93–97. https://doi.org/10.3126/ajms.v11i5.29439

Issue

Vol. 11 No. 5 (2020)

Section

Original Articles

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