Urinary iodine in second trimester of pregnancy: A cross sectional study in tertiary care hospital of Belagavi

Authors

  • Bibek Basnet Post Graduate Student, Department of Biochemistry, KLE Academy of Higher Education and Research, Jawaharlal Nehru Medical College, Belagavi, Karnataka, India https://orcid.org/0000-0001-8464-2315
  • Anuradha Patil Professor & Head, Department of Biochemistry, KLE Academy of Higher Education and Research, Jawaharlal Nehru Medical College, Belagavi, Karnataka, India
  • Shridevi Metgud Assistant Professor, Department of Obstetrics and Gynaecology, KLE Academy of Higher Education and Research, Jawaharlal Nehru Medical College, Belagavi, Karnataka, India
  • Lokjan Singh Post Graduate student, Department of Microbiology, KLE Academy of Higher Education and Research, Jawaharlal Nehru Medical College, Belagavi, Karnataka, India
  • Keshab Parajuli Lecturer, Department of Public Health, Asian College for Advance Studies, Purbanchal University, Nepal
  • Bikram Basnet Department of Radiology, University of South China, Hengyang, Hunan, China

DOI:

https://doi.org/10.3126/ajms.v11i5.29439

Keywords:

Urinary Iodine, Pregnancy, ammomiun persulfate, TSH

Abstract

Background: Iodine is a nutritionally important trace element and its deficiency is a common health problem affecting a huge population, particularly pregnant women and children. The physiological role of iodine in the human body is synthesis of thyroid hormones. Thyroxine is approximately 60% iodine by weight. If iodine intake falls below approximately 100μg/day, Thyroid Stimulating Hormone (TSH) secretion is augmented, which increases plasma inorganic iodide clearance.

Aims and Objective: To correlate urinary iodine with serum TSH in the second trimester of pregnant women.

Material and Methods: One hundred five subjects were included in the study from tertiary care hospital. A random urine sample was collected. Iodine was estimated by ammonium persulfate method and TSH values were collected from the OBG department of the subjects enrolled. Statistics: Pearson correlation coefficient was done.

Results: Median UI 138.50 (29.80-350.51) μg/L, median TSH 1.90(0.17-7.46) mIU/L. There was no significant correlation between UI and serum TSH with r = (0.0873, (p = 0.3756).

Conclusion: Urinary iodine is a marker for population iodine status. A preferable biomarker is necessary to know the iodine status of individual which include not only nutritional biomarker and also required to organise reference range for TSH.

Downloads

Download data is not yet available.
Abstract
183
PDF
235
Cover 11(5)

Downloads

Published

2020-09-01

How to Cite

Basnet, B., Patil, A., Metgud, S., Singh, L., Parajuli, K., & Basnet, B. (2020). Urinary iodine in second trimester of pregnancy: A cross sectional study in tertiary care hospital of Belagavi. Asian Journal of Medical Sciences, 11(5), 93–97. https://doi.org/10.3126/ajms.v11i5.29439

Issue

Vol. 11 No. 5 (2020)

Section

Original Articles

License

Authors who publish with this journal agree to the following terms:

  1. The journal holds copyright and publishes the work under a Creative Commons CC-BY-NC license that permits use, distribution and reprduction in any medium, provided the original work is properly cited and is not used for commercial purposes. The journal should be recognised as the original publisher of this work.
  2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
  3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).