Plasma homocysteine levels in patients with Psoriasis

Authors

  • Mousumi Das Assistant Professor, Department of Biochemistry, Malda Medical College, Malda Town, West Bengal, India http://orcid.org/0000-0002-6698-110X
  • Indranil Dawn Assistant Professor, Department of Biochemistry, Malda Medical College, Malda Town, West Bengal, India http://orcid.org/0000-0002-4152-8421
  • Susmita Sarkar Assistant Professor, Department of Biochemistry, Malda Medical College, Malda Town, West Bengal, India http://orcid.org/0000-0002-9352-7586
  • Kapildev Das Assistant Professor, Department of Dermatology, Malda Medical College, Malda Town, West Bengal, India

DOI:

https://doi.org/10.3126/ajms.v8i5.17136

Keywords:

Homocysteine, Psoriasis, PASI scores

Abstract

Background: Hyper homocysteinaemia represents an independent risk factor for atherosclerotic cardiovascular disease, stroke, peripheral arterial occlusive disease and venous thrombosis. Psoriasis is a chronic inflammatory skin disease associated with increased atherothrombosis and cardiovascular risk profile. Aims and Objective: The aim of this study is to investigate homocysteine in psoriatic patients and its relationship with the severity of the disease.

Materials and Methods: A case control study in 50 patients with chronic plaque psoriasis and 50 healthy controls was performed. Total plasma homocysteine level, and PASI index were assessed in every patient.

Results: Patients with psoriasis had plasma homocysteine levels higher than controls. The severity of psoriasis assessed according to PASI directly correlate either with plasma homocysteine.

Conclusion: A significantly higher prevalence of hyperhomocysteinaemia was found in psoriatic patients compared to healthy controls. Our data directly correlate the high level of homocysteine with higher PASI scores.

Asian Journal of Medical Sciences Vol.8(5) 2017 4-7

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Author Biography

Mousumi Das, Assistant Professor, Department of Biochemistry, Malda Medical College, Malda Town, West Bengal, India

Department of Biochemistry, Assistant Professor

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Published

2017-08-31

How to Cite

Das, M., Dawn, I., Sarkar, S., & Das, K. (2017). Plasma homocysteine levels in patients with Psoriasis. Asian Journal of Medical Sciences, 8(5), 4–7. https://doi.org/10.3126/ajms.v8i5.17136

Issue

Vol. 8 No. 5 (2017)

Section

Original Articles

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