Leukocyte count and C reactive protein as diagnostic factors in febrile convulsion

Authors

  • Garima Biyani Department of Pediatrics, Institute Of Child Health, Kolkata http://orcid.org/0000-0003-0179-4175
  • Swapan Kumar Ray Professor, Department of Peadiatrics ICARE Institute of Medical Sciences and Research, Banbishnupur, Purba Medinipur, Haldia, West Bengal 721645 http://orcid.org/0000-0002-6166-6960
  • Kripasindhu Chatterjee Assistant Professor, Department of Pediatrics ICARE Institute of Medical Sciences and Research, Banbishnupur, Purba Medinipur, Haldia, West Bengal 721645
  • Sukanta Sen Associate Professor, Department of Pharmacology, ICARE Institute of Medical Sciences and Research, Banbishnupur, Purba Medinipur, Haldia, West Bengal 721645
  • Pradyut Kumar Mandal Assistant Professor, Department of Pediatrics ICARE Institute of Medical Sciences and Research, Banbishnupur, Purba Medinipur, Haldia, West Bengal 721645
  • Mallar Mukherjee Assistant Professor, Department of Pediatrics, Institute Of Child Health, Kolkata, West Bengal 700017

DOI:

https://doi.org/10.3126/ajms.v8i2.16331

Keywords:

Seizures, febrile, C reactive protein, Leukocytosis

Abstract

Background: Febrile convulsion (FC) is the most common seizure disorder in childhood. White blood cell (WBC) and C reactive protein (CRP) are commonly measured in FC. Add a paragraph on Aims and Objectives of the study.

Aims and Objectives: To compare WBC and CRP in febrile children, aged 6 months to five years, with and without FC, in order to determine whether leukocytosis and elevated CRP can be used as diagnostic tool for febrile seizure.

Materials and Methods: In this cross sectional study 214 children (112 with FC), aged 6 months to 5 years, admitted to in the first 48 hours of their febrile disease, either with or without seizure, were evaluated over a 12 months period. Age, sex, temperature; WBC, CRP and hemoglobin were recorded in all children. There was a significant increase of WBC (P<0.001) in children with FC so we can deduct that leukocytosis encountered in children with FC can be due to convulsion in itself.

Results: When comparing FC and non-FC children, we encountered a significant increase of WBC (P =0.0005) in children with FC, measured at the time of admission to pediatric medicine ward. There was no significant difference regarding CRP between the two groups. In fact, elevated CRP is a result of underlying pathology.

Conclusion: In stable patients, if there’s no reason to suspect a bacterial infection or who don’t have any indication of lumbar puncture, there’s no need to assess WBC as an indicator of underlying infection. Any child with febrile seizure with a high CRP value should be evaluated for infection.

Asian Journal of Medical Sciences Vol.8(2) 2017 56-58

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Published

2017-03-01

How to Cite

Biyani, G., Ray, S. K., Chatterjee, K., Sen, S., Mandal, P. K., & Mukherjee, M. (2017). Leukocyte count and C reactive protein as diagnostic factors in febrile convulsion. Asian Journal of Medical Sciences, 8(2), 56–58. https://doi.org/10.3126/ajms.v8i2.16331

Issue

Vol. 8 No. 2 (2017)

Section

Original Articles

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