Epicardial fat thickness and carotid intima-media thickness in patients with type 2 diabetes mellitus

Authors

  • Pijush Kanti Mandal Assistant Professor, Department of Medicine, College of Medicine and Sagar Dutta Hospital, Kolkata. http://orcid.org/0000-0001-7182-9711
  • Subhraprakash Pramanik Clinical Tutor, General Medicine, Midnapore Medical College, Midnapore, West Bengal
  • Koushik Mondal RMO Cum Clinical Tutor, Department of General Medicine, Burdwan Medical College, Burdwan, West Bengal
  • Shovan Kumar Das Medical Officer(Specialist), Ghatal SD Hospital, purba Midnapore, West Bengal
  • Arpan Kumar Dey Consultant Physician, Jalpaiguri, West Bengal
  • Samaresh Dutta Junior Resident, Department of General Medicine, College of Medicine and Sagore Dutta Hospital, Kolkata
  • Pranabesh Sarkar Junior Resident, Department of General Medicine, College of Medicine and Sagore Dutta Hospital, Kolkata
  • Amaresh Pramanik Junior Resident, Department of General Medicine, College of Medicine and Sagore Dutta Hospital, Kolkata

DOI:

https://doi.org/10.3126/ajms.v7i6.15543

Keywords:

Epicardial fat thickness (EFT), Carotid intima-media thickness (CIMT), type 2 diabetes mellitus (T2DM).

Abstract

Background: Epicardial adipose tissue thickness has been considered to be a possible cardiovascular risk indicator in recent reports. Aim of this study was to evaluate the relationship of echocardiographic epicardial fat thickness (EFT) with carotid intima-media thickness (CIMT), in patients with type 2 diabetes mellitus (T2DM).

Materials and Methods: In this hospital based cross sectional observational study a total of 64 patients with T2DM (mean age 54.51±6.60 years and 75.0% male) and 76 age and sex-matched non-diabetic control (mean age 54.97±6.11years and 71.1% male) were evaluated. Echocardiographic EFT and ultrasonographic CIMT were measured in all subjects.

Results: Patients with T2DM had significantly increased EFT and CIMT than those of the non-diabetic controls (6.15±0.99 mm versus 4.39±0.61 mm, P< 0.001 and 0.77±0.09 mm versus 0.51±0.05 mm, P< 0.001, respectively). EFT was correlated with CIMT (r = 0.724, P < 0.001), duration of diabetes (r = 0.723, P < 0.001) and fasting plasma glucose level (r = 0.542, P < 0.001). Linear regression analysis showed that CIMT (β = 0.358, t = 3.658, P < 0.001) duration of diabetes (β = 0.324, t = 3.268, P = 0.001) and fasting plasma glucose level (β = 0.210, t = 3.302, P = 0.001) were found to be the independent predictors of EFT.

Conclusion: The echocardiographic EFT was significantly higher in patients with T2DM; and it was well correlated with CIMT, duration of diabetes and fasting plasma glucose level as being the independent predictors of EFT.

Asian Journal of Medical Sciences Vol.7(6) 2016 1-5

Downloads

Download data is not yet available.
Abstract
778
PDF
760

Author Biographies

Pijush Kanti Mandal, Assistant Professor, Department of Medicine, College of Medicine and Sagar Dutta Hospital, Kolkata.

Assistant Professor, Department of General Medicine, College of Medicine and Sagar Dutta Hospital, Kolkata

Subhraprakash Pramanik, Clinical Tutor, General Medicine, Midnapore Medical College, Midnapore, West Bengal

Clinical Tutor, General Medicine, Midnapore Medical College, Midnapore, West Bengal

Koushik Mondal, RMO Cum Clinical Tutor, Department of General Medicine, Burdwan Medical College, Burdwan, West Bengal

Clinical Tutor, General Medicine, Burdwan Medical College, Burdwan, West Bengal

Shovan Kumar Das, Medical Officer(Specialist), Ghatal SD Hospital, purba Midnapore, West Bengal

Medical Officer(Specialist), Ghatal SD Hospital, purba Midnapore, West Bengal

Arpan Kumar Dey, Consultant Physician, Jalpaiguri, West Bengal

Consultant Physician, Jalpayguri, West Bengal

Samaresh Dutta, Junior Resident, Department of General Medicine, College of Medicine and Sagore Dutta Hospital, Kolkata

Junior Resident, General Medicine, College of Medicine and Sagore Dutta Hospital, Kolkata

Pranabesh Sarkar, Junior Resident, Department of General Medicine, College of Medicine and Sagore Dutta Hospital, Kolkata

Junior Resident, General Medicine, College of Medicine and Sagore Dutta Hospital, Kolkata

Amaresh Pramanik, Junior Resident, Department of General Medicine, College of Medicine and Sagore Dutta Hospital, Kolkata

Junior Resident, General Medicine, College of Medicine and Sagore Dutta Hospital, Kolkata

Downloads

Published

2016-10-31

How to Cite

Mandal, P. K., Pramanik, S., Mondal, K., Das, S. K., Dey, A. K., Dutta, S., Sarkar, P., & Pramanik, A. (2016). Epicardial fat thickness and carotid intima-media thickness in patients with type 2 diabetes mellitus. Asian Journal of Medical Sciences, 7(6), 1–5. https://doi.org/10.3126/ajms.v7i6.15543

Issue

Section

Original Articles