Normative data of Visual Evoked Potential in children and correlation with age

Authors

  • Renu Yadav Lecturer, Department of Physiology, Nobel Medical College, Biratnagar http://orcid.org/0000-0002-8126-6585
  • Bishnu Hari Poudel Professor, Department of Basic and Clinical Physiology, B.P. Koirala Institute of Health Sciences, Dharan
  • Nirmala Limbu Additional Professor, Department of Basic and Clinical Physiology, B.P. Koirala Institute of Health Sciences, Dharan
  • Dilip Thakur Associate Professor, Department of Basic and Clinical Physiology, B.P. Koirala Institute of Health Sciences, Dharan
  • Subodh Kumar Yadav Assistant Professor, Department of Anatomy, Nobel Medical College, Biratnagar

DOI:

https://doi.org/10.3126/ajms.v7i2.13135

Keywords:

Visual Evoked Potential, Latency, P120, N90, LED

Abstract

Background: Visual Evoked Potential is the assessment of the visual pathway and the visual cortex. The present study was descriptive analysis of normal VEP between the age of 6 months to 4 years of age and the determination of the neuronal development among healthy children of above age group.

Materials and Methods: The study was conducted in neurological lab of BPKIHS on healthy children (n=36) of well-baby clinic between the age of 0.5 to ≤4 years (yr). Subjects were divided into subgroup 1(0.5 to ≤2 yr), subgroup 2(2 to ≤3 yr) and subgroup 3(3 to ≤4 yr). Visual stimulator provided with flash light emitting diode (LED) goggle was used to stimulate the retina and VEP recording was done. Flash VEP parameters: latencies (N90, P120) and amplitude (N90-P120) were recorded. Post hoc (Bonferroni) analysis was done for comparing VEP variables. Pearson correlation and scatter plot with trend line analysis were done for VEP with respect to age

Results: VEP latencies of children, age-group 3 to Μ4 yr showed significantly less N90 latency on right eye stimulation comparing age-group 0.5 to Μ2 yr (103.75±22.54 vs. 79.09±17.77ms, p=0.012). P120 latency was significantly less on right eye stimulation (148.5±15.38 vs. 116.67±13.65ms p=0.001) and on left eye stimulation (145.91±18.11 vs. 116.67±13.65 ms, p=0.001) in age-group 3 to Μ4 yr children as compared to age-group 0.5 to Μ2 yr.

Conclusion: Significant decrement of VEP latencies as age advances which explains the maturation of central nervous system and functionally approaching to adult value at around 3 to 4 yr.

Asian Journal of Medical Sciences Vol.7(2) 2015 39-43

Downloads

Download data is not yet available.
Abstract
1443
PDF
1712

Downloads

Published

2015-11-05

How to Cite

Yadav, R., Poudel, B. H., Limbu, N., Thakur, D., & Yadav, S. K. (2015). Normative data of Visual Evoked Potential in children and correlation with age. Asian Journal of Medical Sciences, 7(2), 39–43. https://doi.org/10.3126/ajms.v7i2.13135

Issue

Vol. 7 No. 2 (2016)

Section

Original Articles

License

Authors who publish with this journal agree to the following terms:

  1. The journal holds copyright and publishes the work under a Creative Commons CC-BY-NC license that permits use, distribution and reprduction in any medium, provided the original work is properly cited and is not used for commercial purposes. The journal should be recognised as the original publisher of this work.
  2. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
  3. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).