Viral Diarrhoea in Children of Dhulikhel Hospital, Nepal and Medical University of Innsbruck, Austria

Authors

  • Anish Joshi Dhulikhel Hospital Kathmandu University Hospital
  • Ranendra Prakash Bahadur Shrestha Dhulikhel Hospital Kathmandu University Hospital

DOI:

https://doi.org/10.3126/acclm.v2i1.13769

Keywords:

Children, diarrhoea, rotavirus, vaccine

Abstract

BACKGROUND
Viral diarrhoea is still a major cause of childhood morbidity and mortality worldwide, with high morbidity in children younger than 5 years of age particularly in developing countries. The objective of this study was to determine the frequency of viral diarrhoea in children less than 5 years of age at Kathmandu University Hospital/Dhulikhel Hospital (DH), Nepal and Medical University of Innsbruck (MUI), Austria and to compare the clinical presentation and the common cause of acute childhood diarrhoea in the two institutions.

METHODS
This was a hospital based, comparative study done in two different hospitals DH and MUI. A total of 200 cases of under 5 years old children, among which 100 cases attending DH from 1st December 2011 to 29th February 2012 and 100 cases attending MUI from 1st March 2012 to 31st May 2012, presented with acute onset of diarrhoea were enrolled in the study. The fresh stool specimens were analysed in the laboratory of individual hospital in order to examine the common pathogens.

RESULTS
Majority of children were classified as no dehydration (DH: 75% and MUI: 74%); in DH 5% were classified as severe dehydration, whereas in MUI it was null. In MUI, 96% of children were brought within 3 days of illness, whereas only 32% were brought in DH which was statistically significant (p=<0.001). In DH 37% of cases required hospital admission, among which 7 cases needed PICU, whereas in MUI, 52% of cases were admitted (p=0.03); and no cases needed PICU. The mean hospital stay was 1.1±1.7 days and 1.3±1.8 days in DH and MUI, respectively. Rotavirus was positive in significant number of cases in DH (66%) (p=<0.001). Other pathogen detected in DH was Adenovirus (13%). The most common pathogen detected in MUI was Norovirus (16%), followed by Rotavirus (11%) and Adenovirus (9%).

CONCLUSIONS
Incidence of acute diarrhoea was highest below 24 months of age. Rotavirus and Norovirus was the most common cause of children diarrhoea in Nepal and Austria, respectively. 

Downloads

Download data is not yet available.
Abstract
828
PDF
1598

Author Biographies

Anish Joshi, Dhulikhel Hospital Kathmandu University Hospital

Lecturer, Pediatrician, Department of Pediatrics

Ranendra Prakash Bahadur Shrestha, Dhulikhel Hospital Kathmandu University Hospital

Professor, Head of Department, Department of Pediatrics

Downloads

Published

2016-05-03

How to Cite

Joshi, A., & Shrestha, R. P. B. (2016). Viral Diarrhoea in Children of Dhulikhel Hospital, Nepal and Medical University of Innsbruck, Austria. Annals of Clinical Chemistry and Laboratory Medicine, 2(1), 11–18. https://doi.org/10.3126/acclm.v2i1.13769

Issue

Vol. 2 No. 1 (2016)

Section

Original Articles

License

Authors who publish with this journal agree to the following terms:

  1. The author transfers copyright to the Nepalese Association for Clinical Chemistry.
  2. The journal publishes the work under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal and under the same share-alike license used here.
  3. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
  4. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).