Alumina Supported Synthesis of Some α,β– Unsaturated Heterocyclic Acids

Authors

  • A. D. Mishra Department of Chemistry, Tribhuvan University, P.N. Campus, Pokhara

DOI:

https://doi.org/10.3126/jncs.v29i0.9229

Keywords:

Solid support, Microwave irradiations, Condensation, Decarboxylation, One pot synthesis, Heterocyclic acids

Abstract

Solid supported synthesis of some novel 3- (5'- substituted-2-furyl/thienyl) propen -2- oic acids has been carried out from malonic acid and 5- substituted furan/thiophene-2-carboxaldehydes under microwave irradiations in solvent free condition. The reaction completed in one step via condensation affording 88-96% of yield within 4-6 minutes. The reactions are accompanied with easy work-up, limited use of organic solvents and the use of inexpensive and hazard- free chemicals. 

DOI: http://dx.doi.org/10.3126/jncs.v29i0.9229

Journal of Nepal Chemical Society

Vol. 29, 2012

Page: 1-4

Uploaded date : 12/3/2013

 

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Published

2013-12-03

How to Cite

Mishra, A. D. (2013). Alumina Supported Synthesis of Some α,β– Unsaturated Heterocyclic Acids. Journal of Nepal Chemical Society, 29, 1–4. https://doi.org/10.3126/jncs.v29i0.9229

Issue

Vol. 29 (2012)

Section

Articles

License

© Journal of Nepal Chemical Society