Incidence and impact on prognosis of heart failure in Middle Eastern patients undergoing percutaneous coronary interventions

Authors

  • Ayman J Hammoudeh Interventional Cardiologist, Department of Cardiology, Istishari Hospital http://orcid.org/0000-0003-4940-2679
  • Dalal Al-Natour Medical Pharmacist, Department of Pharmacy services, Jordan Hospital, Queen Noor, Amman
  • Yousef Khader Professor of Public Health, School of Allied Medical Sciences, Jordan University of Science and Technology, Irbid.
  • Imad A Alhaddad Interventional Cardiologist, Department of Cardiology, Jordan Hospital, Queen Noor Street, Amman, Jordan
  • Ramzi Tabbalat Interventional Cardiologist, Department of Cardiology, Khalidi Medical Center, Ibn Khaldoun Street, Amman, Jordan http://orcid.org/0000-0003-2628-9618
  • Eyas Al-Mousa Assistant Professor, Cardiology Section, Internal Medicine Department, Jordan University Hospital, Queen Rania Street, and Interventional Cardiologist, Department of Cardiology, Istishari Hospital
  • Akram Saleh Professor of Medicine, Cardiology Section, Internal Medicine Department, JordanUniversity Hospital, Amman, Jordan

DOI:

https://doi.org/10.3126/ajms.v8i2.15872

Keywords:

Heart failure, Percutaneous coronary intervention, Outcome, Prognosis

Abstract

Background:  Heart failure (HF) is a serious complication of percutaneous coronary intervention (PCI) that adversely impacts survival and quality of life.  

Aims and Objectives: We sought to study the incidence of HF in Middle Eastern patients undergoing PCI and its impact on prognosis.

Materials and Methods: The first Jordanian PCI Registry was a prospective multicenter study of PCI patients who were followed for one year. Patients who developed heart failure during hospitalization had their clinical and coronary angiographic profiles and adverse outcomes compared with those in patients who did not develop HF. 

Results: Of 2425 patients who had PCI, 194 (8.0%) developed HF during the hospital stay. Compared with patients who did not develop HF, those who developed HF were more likely to have diabetes mellitus, prior history of myocardial infarction (MI), elevated levels of cardiac biomarkers, ST-segment elevation MI and multivessel or left anterior descending coronary artery disease (all p values<0.05). Cardiac mortality was significantly higher among patients who developed HF compared with those who did not (5.2% vs. 0.4%; p<0.0001) and at one year (11.2% vs. 1.2%; p<0.001). Multivariate analysis showed that HF during hospital stay was an independent predictor of one-year cardiac mortality (Odds ratio 6.1, 95% CI 3.3-11.1, p<0.001) . At one year, readmission rates for HF and ACS were higher among HF patients. 

Conclusions: Certain clinical and angiographic features were associated with higher incidence of HF among Middle Eastern patients who undergo PCI. HF was associated with higher risk of death and other adverse cardiac events during hospital stay and one year of follow up.

Asian Journal of Medical Sciences Vol.8(2) 2017 20-28

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Author Biography

Dalal Al-Natour, Medical Pharmacist, Department of Pharmacy services, Jordan Hospital, Queen Noor, Amman

Clinical Pharmacist

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Published

2017-03-01

How to Cite

Hammoudeh, A. J., Al-Natour, D., Khader, Y., Alhaddad, I. A., Tabbalat, R., Al-Mousa, E., & Saleh, A. (2017). Incidence and impact on prognosis of heart failure in Middle Eastern patients undergoing percutaneous coronary interventions. Asian Journal of Medical Sciences, 8(2), 20–28. https://doi.org/10.3126/ajms.v8i2.15872

Issue

Vol. 8 No. 2 (2017)

Section

Original Articles

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